Entries by ImmProNano

Shared immunoproteome for ovarian cancer diagnostics and immunotherapy: potential theranostic approach to cancer.

J Proteome Res. 2007 Jul;6(7):2509-17. Epub 2007 Jun 5. Philip R1, Murthy S, Krakover J, Sinnathamby G, Zerfass J, Keller L, Philip M. 1Immunotope Inc., The Pennsylvania Biotechnology Center, 3805 Old Easton Road, Doylestown, Pennsylvania 18902, USA. Abstract Elimination of cancer through early detection and treatment is the ultimate goal of cancer research and is […]

Evaluation of novel particles as pulmonary delivery systems for insulin in rats.

AAPS PharmSci. 2003;5(2):E9. Garcia-Contreras L1, Morçöl T, Bell SJ, Hickey AJ. 1Division of Drug Delivery and Disposition, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. lgarciac@email.unc.edu Abstract The purpose of the study was to evaluate the influence of calcium phosphate (CAP) and polyethylene glycol (PEG) particles on the systemic delivery of […]

Calcium phosphate nanoparticles induce mucosal immunity and protection against herpes simplex virus type 2.

Clin Diagn Lab Immunol. 2002 Sep;9(5):1021-4. He Q1, Mitchell A, Morcol T, Bell SJ. 1BioSante Pharmaceuticals, Inc., Smyrna, Georgia 30082, USA. qinghe@bellsouth.net Abstract Previously we reported that calcium phosphate nanoparticles (CAP) represented a superior alternative to alum adjuvants in mice immunized with viral protein. Additionally, we showed that CAP was safe and elicited no detectable […]

Calcium phosphate nanoparticle adjuvant.

Clin Diagn Lab Immunol. 2000 Nov;7(6):899-903. He Q1, Mitchell AR, Johnson SL, Wagner-Bartak C, Morcol T, Bell SJ. 1BioSante Pharmaceuticals, Inc., Smyrna, Georgia 30082, USA. biosante@bellsouth.net Abstract Vaccination to protect against human infectious diseases may be enhanced by using adjuvants that can selectively stimulate immunoregulatory responses. In a murine model, a novel nanoparticulate adjuvant composed […]

Further Publications

Joseph D. Comber, Aykan Karabudak, Xiaofang Huang, Paolo A. Piazza, Ernesto T.A. Marques, and Ramila Philip. Dengue virus specific dual HLA binding T cell epitopes induce CD8+ T cell responses in seropositive individuals.  Human vaccines and immunotherapeutics.  Human Vaccines & Immunotherapeutics.  2014, 10:12, 3531-3543, DOI: 10.4161/21645515.2014.980210 Joseph D. Comber, Aykan Karabudak, Vivekananda Shetty, James S. […]